Exeter are starting to click into gear with the midweek win at Leyton Orient making it three games without defeat and three clean sheets in the process.
The Grecians are now within two points of the play-offs and couldn't ask for a better fixture on paper right now.
Their season might be less than two months old, but Cambridge look in serious trouble after losing seven of their first eight fixtures.
As a result, the U's travel to St James' Park already seven points from safety.