Salford's 1-1 draw with Crewe at the weekend was their second successive draw, and they have now failed to win in their last five games and only won one of their last 12.
Chesterfield's 2-1 win over Newport at the weekend ended four straight defeats for the Spireites.
Only five points separate Chesterfield in 15th and Salford in 11th.
This will be just the second Football League meeting between Salford City and Chesterfield after the pair drew 1-1 in the reverse fixture back in August.
Salford boss Karl Robinson has only lost one of his six previous managerial games against Chesterfield in the Football League.